• Article
• Open access
• Published: 16 July 2026

Multiomic profiling links L1 retrotransposition to genomic instability and ecDNA in bladder cancer

• Sophia J. Pribus^1,2 na1,
• Ivana Osredek^1,3 na1,
• Jan Otoničar^3,4 na1,
• Milena Simovic-Lorenz 
  ORCID: orcid.org/0000-0001-8835-6885^4 na1,
• Chiara Giovenino 
  ORCID: orcid.org/0000-0003-2041-4019^3,4,
• Anne Rademacher 
  ORCID: orcid.org/0000-0003-3054-3121⁵,
• Sina Jasmin Wille 
  ORCID: orcid.org/0009-0000-1254-7431⁵,
• Cecilia Berzain Battioni⁴,
• Michael Scherer 
  ORCID: orcid.org/0000-0001-7990-6179⁶,
• Sergio Manzano-Sanchez 
  ORCID: orcid.org/0009-0006-5460-5824⁶,
• Andreas Kienzle 
  ORCID: orcid.org/0009-0008-4142-3196^7,8,
• Urja Parekh^3,4,
• Laura Villacorta⁹,
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